| Samurai Shodown! 2 | SNK | 6/10 | |
| Secret Files 2: Puritas Cordis | Deep Silver | 8/10 | |
| Secrets of the Titanic: 1912-2012 | Avanquest | 3/10 | |
| SEGA AGES Puyo Puyo 2 | SEGA | 8/10 | |
| SEGA Ages: Columns 2: A Voyage Through Time | SEGA | 7/10 | |
| SEGA AGES: Sonic the Hedgehog 2 | SEGA | 9/10 | |
| Senran Kagura 2: Deep Crimson | Marvelous | 8/10 | |
| Shin Megami Tensei Liberation Dx2 | SEGA | 8/10 | |
| Shin Megami Tensei: Devil Survivor 2 - Record Breaker | NIS America | 9/10 | |
| Shin Megami Tensei: Devil Survivor 2 - Record Breaker (Second Opinion) | NIS America | 8/10 | |
| Shovel Knight Dig | Yacht Club | 8/10 | |
| Silent Hill 2 | Konami | 8/10 | |
| Silent Hill 2 | Konami | 8/10 | |
| Skullgirls 2nd Encore | Autumn | 9/10 | |
| Solomon’s Key 2 | Tecmo | 6/10 | |
| Sonic Advance 2 | SEGA | 9/10 | |
| Sonic Adventure 2 | SEGA | 5/10 | |
| Sonic Adventure 2 Battle | SEGA | 6/10 | |
| Sonic the Hedgehog 2 | SEGA | 8/10 | |
| Sorcery! 2 | Arc System Works | 8/10 | |
| Sorcery! 2 | inkle | 7/10 | |
| Sorcery! Parts 1 & 2 | inkle | 7/10 | |
| Soul Hackers 2 | Atlus | 8/10 | |
| Space Pirates and Zombies 2 | MinMax Games | 6/10 | |
| Sparkle 2 | 10tons | 7/10 | |
| Spider-Man 2 | Activision | 8/10 | |
| Splatoon 2 | Nintendo | 8/10 | |
| Splatoon 2: Octo Expansion | Nintendo | 8/10 | |
| Star Fox 2 | Nintendo | 5/10 | |
| StarDrive 2 | Iceberg | 6/10 | |
| Starpoint Gemini 2 | Iceberg | 6/10 | |
| Starpoint Gemini 2 (Second Opinion) | Iceberg | 7/10 | |
| Stealth Inc. 2: A Game of Clones | Curve | 9/10 | |
| Stealth Inc. 2: A Game of Clones | Curve Digital | 2/10 | |
| SteamWorld Dig | Image & Form | 9/10 | |
| SteamWorld Dig | Image & Form | 8/10 | |
| SteamWorld Dig | Image & Form | 8/10 | |
| SteamWorld Dig | Image & Form | 8/10 | |
| SteamWorld Heist | Image & Form | 9/10 | |
| SteamWorld Heist | Image & Form | 8/10 | |
| SteamWorld Heist | Image & Form | 9/10 | |
| SteamWorld Heist | Image & Form | 7/10 | |
| SteamWorld Heist II | Thunderful | 9/10 | |
| SteamWorld Heist: Ultimate Edition | Image & Form | 9/10 | |
| Super Bomberman R 2 | Konami | 8/10 | |
| Super Mario Galaxy 2 | Nintendo | 10/10 | |
| Super Mario Land 2: 6 Golden Coins | Nintendo | 8/10 | |
| Super Mario Maker 2 | Nintendo | 9/10 | |
| Super Mario Maker 2 (Second Opinion) | Nintendo | 7/10 | |
| Super Mario World 2: Yoshi's Island | Nintendo | 9/10 | |
| Super Steampunk Pinball 2D | Devonian | 6/10 | |
| Supreme Commander 2 | Square Enix | 6/10 | |
| Supreme League of Patriots Issue 2 - Patriot Frames | Phoenix Online Publishing | 7/10 | |
| Syberia 2 | Microids | 7/10 | |